Trends in Arrhythmia-Related Mortality Associated With Congenital Heart Disease in the United States
Authors' conclusion
Arrhythmia-related mortality associated with CHD declined over 26 years, but progress has stalled or reversed since 2012, especially among the elderly, certain regions, and racial groups.
Study context
- Population
- Arrhythmia-related deaths involving congenital heart disease (CHD) as a contributing cause of death in the United States, 1999 to 2024arrhythmia-related deaths involving documented CHD
- Participants
- 24,711 deaths
- Outcome
- Overall AAMR
- Follow-up
- 1999 to 2024
Methodological detailsmultiple cause-of-death records, Joinpoint regression, exploratory ARIMA projections through 2034
- Multiple cause-of-death records
- Joinpoint regression
- Exploratory ARIMA projections through 2034
Main finding
As reported in the abstract
AAMR in 1999
0.42
AAMR in 2024
0.30
Observational data: associations, not effects.
Further findings
AAMR by sex
- Males had consistently higher mortality
AAMR by race/ethnicity
- All racial groups showed declines, but non-Hispanic Black individuals had the highest rates
AAMR by urbanization
- Large metropolitan areas experienced the most rapid decline, while rural areas had persistently elevated mortality
AAMR by age
- Infants had the highest mortality, while ages 15 to 24 showed the fastest decline
- Adults ≥55 years of age demonstrated increasing mortality beginning in the mid-2000s, most prominently in those 75-84 years of age
Exploratory projections of overall AAMR · through 2034
- Overall AAMR will stabilize around
- 0.30
- Continued increases in the 75-84-year group
- Exploratory
Original publication
Trends in Arrhythmia-Related Mortality Associated With Congenital Heart Disease in the United States. JACC Adv. Published 18 August 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →