Heart failure & cardiomyopathiesCohort study
Trends in Heart Failure Mortality in Sweden Between 1997 and 2022
- Nationwide registry-based cohort study
Authors' conclusion
Heart failure-related mortality has declined over the last ~25 years in Sweden. All-cause mortality in patients with HF has also declined, more in HF with reduced than preserved EF, mirroring the different availability of life-saving treatments across the EF spectrum.
Study context
- Population
- Swedish national population and patients with incident heart failure (HF), 1997–2022
- Outcome
- Temporal trends in HF-related mortality (national population) and all-cause mortality after incident HF diagnosis, overall and by EF
Main finding
As reported in the abstract
Age-adjusted HF-related mortality, general population · 1997 to 2022
Declined from 33.4 to 23.8 per 100 000 individuals
AAPC −2.15%, p < 0.001
Observational data: associations, not effects.
Further findings
All-cause mortality after first HF diagnosis, National Patient Register (NPR) cohort (n = 423 092) · 2022
- 1-year mortality
- 25%
- 3-year mortality
- 46%
- 5-year mortality
- 58%
- Decline in 1-year mortality over time, regardless of age or sex
- Average annual percentage change (AAPC) −1.10%, p < 0.001
Decline in 1-year mortality by ejection fraction (EF), SwedeHF (n = 63 753)
- EF <40%
- AAPC −2.64%, p < 0.001
- EF 40-49%
- AAPC −2.30%, p = 0.062
- EF ≥50%
- AAPC −2.16%, p = 0.032
- decline less steep with increasing EF
Original publication
Trends in Heart Failure Mortality in Sweden Between 1997 and 2022. Eur J Heart Fail. Published 28 October 2024. doi:10.1002/ejhf.3506
Summarised from the published abstract; every number is checked against it