Heart failure & cardiomyopathies
Prognostic Value of Hypoxaemic Burden from Overnight Oximetry in Heart Failure with Preserved Ejection Fraction
Authors' conclusion
Nocturnal hypoxaemic burden is an independent prognostic marker for the composite of HF hospitalisations or all-cause mortality in HFpEF.
Study context
- Population
- Patients with HF with preserved ejection fraction (HFpEF) from a specialised outpatient clinic, ambulatory home sleep monitoring
- Participants
- 126 patients
- Exposure
- Nocturnal hypoxaemic burden and outcomes
- Outcome
- Composite of:
- Heart failure (HF) hospitalisations
- All-cause mortality
- Follow-up
- Median 34 months [IQR 18.4-52.0]
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
median 34 months
Hazard ratio (95% CI)P value
T90 per 1 min increase
1.004(1.001–1.007)
P = 0.019T90 per 1 h increase
1.265(1.061–1.488)
Each row per its own increment, as printed
- Patients reaching composite endpoint
- 32 (25%)
Observational data: associations, not effects.
Further findings
Nocturnal hypoxaemic burden (T90)
- Median T90
- 13.7 min
- Oxygen saturation at no time below 90%
- 10 (7.9%)
Original publication
Prognostic Value of Hypoxaemic Burden from Overnight Oximetry in Heart Failure with Preserved Ejection Fraction. ESC Heart Fail. Published 27 October 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →