Tricuspid Valve Academic Research Consortium-2 (TVARC-2)): Trial Design and Endpoints

Davidson, CJ; Hahn, RT; Mehaffey, JH; Cohen, DJ; Pinney, SP; Arnold, SV; Stolz, L; Lawlor, MK; Lindenfeld, J; Brener, MI; Afzal, AM; Smith, RL; White, RM; Vemulapalli, S; Alu, MC; Cohen, E; Regan, K; Sannino, A; Elmariah, S; Spitzer, E; Blackstone, EH; Lurz, P; Lindman, BR; Topilsky, Y; Baron, SJ; Chadderdon, S; Khalique, OK; Tang, GHL; Taramasso, M; Grayburn, PA; Badano, L; Leipsic, J; Windecker, S; Redfors, B; Rodés-Cabau, J; Ben-Yehuda, O; Ailawadi, G; Mack, MJ; Leon, MB; Badhwar, V; Hausleiter, J

doi:10.1016/j.jacc.2026.02.5102

Valvular & structural heart disease

Tricuspid Valve Academic Research Consortium-2 (TVARC-2)): Trial Design and Endpoints

J Am Coll CardiolPublished 21 Apr 2026Academic Research Consortium document

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Defines specific trial design and endpoint options for comparisons of emerging technologies, tricuspid valve surgery and medical therapy

Reference

Issued by: Tricuspid Valve Academic Research Consortium
Document: Academic research consortium consensus document (second chapter)
Scope: Trial design and endpoint options for comparisons of emerging transcatheter technologies, tricuspid valve surgery and medical therapy in tricuspid regurgitation

Authors: Davidson CJ, Hahn RT, Mehaffey JH, Cohen DJ, Pinney SP, Arnold SV, et al.
All 41 authors
Davidson CJ, Hahn RT, Mehaffey JH, Cohen DJ, Pinney SP, Arnold SV, Stolz L, Lawlor MK, Lindenfeld J, Brener MI, Afzal AM, Smith RL, White RM, Vemulapalli S, Alu MC, Cohen E, Regan K, Sannino A, Elmariah S, Spitzer E, Blackstone EH, Lurz P, Lindman BR, Topilsky Y, Baron SJ, Chadderdon S, Khalique OK, Tang GHL, Taramasso M, Grayburn PA, Badano L, Leipsic J, Windecker S, Redfors B, Rodés-Cabau J, Ben-Yehuda O, Ailawadi G, Mack MJ, Leon MB, Badhwar V, Hausleiter J
Journal: JACC
Published: 21 Apr 2026
DOI: 10.1016/j.jacc.2026.02.5102
PubMed: 42017555

Topic: Valvular & structural heart disease

Original publication

Tricuspid Valve Academic Research Consortium-2 (TVARC-2)): Trial Design and Endpoints. J Am Coll Cardiol. Published 21 April 2026. doi:10.1016/j.jacc.2026.02.5102

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