Coronary disease & ACS

Triglyceride-Glucose Index’s Link to Cardiovascular Outcomes Post-Percutaneous Coronary Intervention in China: A Meta-Analysis

ESC Heart FailPublished Systematic review and meta-analysis

Pooled result · MACEResult — go to the resultHazard ratio 2.04 95% CI 1.65–2.52

Authors' conclusion

The TyG index may predict risks of post-PCI MACE, all-cause mortality, non-fatal MI, and revascularization, with varied levels of certainty.

Study context

Population
Patients after percutaneous coronary intervention (PCI) in China
Comparison
Highest vs lowest triglyceride-glucose (TyG) index
Outcome
MACE
Methodological detailsrandom-effects models, dose-response analysis, GRADE, Embase, PubMed, Cochrane Library and Web of Science searched up to 3 March 2023
  • Random-effects models
  • Dose-response analysis
  • GRADE
  • Embase, PubMed, Cochrane Library and Web of Science searched up to 3 March 2023

Pooled result

As reported in the abstract

Hazard ratio

2.04

95% CI 1.65–2.52

Highest TyG indexvs Lowest TyG index
HR 2.04 (95% CI 1.65–2.52)

Further pooled results

OutcomeHR (95% CI)
MACE per unit increase in TyG indexI2 = 92% · low certainty (GRADE)1.82 (1.34–2.46)
Non-fatal MI per unit increase in TyG indexI2 = 63% · high certainty (GRADE)2.57 (1.49–4.41)
Revascularization per unit increase in TyG indexI2 = 90% · low certainty (GRADE)2.06 (1.23–3.50)

All-cause mortality

HR (95% CI)
Elevated TyG indexI2 = 50% · low certainty (GRADE)1.93 (1.35–2.75)

Dose-response: TyG index and major adverse cardiovascular events (MACE) risk

Linear relationship (R2)
0.6114

Original publication

Triglyceride-Glucose Index’s Link to Cardiovascular Outcomes Post-Percutaneous Coronary Intervention in China: A Meta-Analysis. ESC Heart Fail. Published 21 January 2024. doi:10.1002/ehf2.14679

Composed by AI from the published abstract and checked against it. How Briefs are made →

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