Triglyceride-Glucose Index’s Link to Cardiovascular Outcomes Post-Percutaneous Coronary Intervention in China: A Meta-Analysis
Pooled result · MACEResult — go to the resultHazard ratio 2.04 95% CI 1.65–2.52Authors' conclusion
The TyG index may predict risks of post-PCI MACE, all-cause mortality, non-fatal MI, and revascularization, with varied levels of certainty.
Study context
- Population
- Patients after percutaneous coronary intervention (PCI) in China
- Comparison
- Highest vs lowest triglyceride-glucose (TyG) index
- Outcome
- MACE
Methodological detailsrandom-effects models, dose-response analysis, GRADE, Embase, PubMed, Cochrane Library and Web of Science searched up to 3 March 2023
- Random-effects models
- Dose-response analysis
- GRADE
- Embase, PubMed, Cochrane Library and Web of Science searched up to 3 March 2023
Pooled result
As reported in the abstract
Hazard ratio
2.04
95% CI 1.65–2.52
Highest TyG indexvs Lowest TyG index
HR 2.04 (95% CI 1.65–2.52)
Further pooled results
| Outcome | HR (95% CI) | |
|---|---|---|
| MACE per unit increase in TyG indexI2 = 92% · low certainty (GRADE) | 1.82 (1.34–2.46) | |
| Non-fatal MI per unit increase in TyG indexI2 = 63% · high certainty (GRADE) | 2.57 (1.49–4.41) | |
| Revascularization per unit increase in TyG indexI2 = 90% · low certainty (GRADE) | 2.06 (1.23–3.50) | |
| 0.20.5125Hazard ratio (log scale) |
All-cause mortality
| HR (95% CI) | ||
|---|---|---|
| Elevated TyG indexI2 = 50% · low certainty (GRADE) | 1.93 (1.35–2.75) | |
| 0.20.5125Hazard ratio (log scale) |
Dose-response: TyG index and major adverse cardiovascular events (MACE) risk
- Linear relationship (R2)
- 0.6114
Original publication
Triglyceride-Glucose Index’s Link to Cardiovascular Outcomes Post-Percutaneous Coronary Intervention in China: A Meta-Analysis. ESC Heart Fail. Published 21 January 2024. doi:10. 1002/ ehf2. 14679
Composed by AI from the published abstract and checked against it. How Briefs are made →