Acute cardiac care & resuscitationCohort study
Understanding patients with mechanical circulatory support for cardiogenic shock: The role of preceding cardiac arrest
- real-world AMICS cohort
- Netherlands Heart Registration (NHR) PCI Registry
- nine hospitals
- 2017 and 2021
Authors' conclusion
Although 30-day mortality rates were comparable, determinants of mortality differed between OHCA and non-OHCA patients. This study highlights the importance of distinguishing between OHCA and non-OHCA, and emphasises that OHCA alone should not be a contraindication for MCS or MCS-evaluating trials.
Study context
- Population
- Patients with myocardial infarction-related cardiogenic shock (AMICS) who underwent PCI and received mechanical circulatory support (MCS)patients included, mean age 59.7 years, 78.0% male
- Participants
- 241 patients
- Exposure
- OHCA vs non-OHCA
- OHCAn = 119
Main finding
As reported in the abstract
Thirty-day mortality · 30 days
P = 0.869
Observational data: associations, not effects.
Further findings
Patient profile, OHCA vs non-OHCA
- OHCA patients had a better pre-existing condition, a more acute presentation and less frequent multivessel disease
Predictors of 30-day mortality, overall cohort
- age, lactate, intubation and multivessel disease were independently associated with 30-day mortality
Predictors of 30-day mortality, OHCA patients
- age and lactate lost predictive value; resuscitation longer than 30 min, an initial non-shockable rhythm, and multivessel disease were strongly associated with mortality
Predictors of 30-day mortality, non-OHCA patients
- age, lactate and in-hospital cardiac arrest were predictive, while multivessel disease was not associated with 30-day mortality
Original publication
Understanding patients with mechanical circulatory support for cardiogenic shock: The role of preceding cardiac arrest. Resuscitation. Published 25 May 2026. doi:10.1016/j.resuscitation.2026.111149
Summarised from the published abstract; every number is checked against it