Arrhythmias & electrophysiologyCohort study
Upgrading expandable leadless pacemakers from single- to dual-chamber
- Prospective single-group study (upgrade analysis)
- multicentre
- Followed 12 months from attempted atrial leadless pacemaker (LP) implantation
Authors' conclusion
These data confirm the feasibility, safety, and long-term effectiveness of adding an atrial LP in patients with a pre-existing ventricular LP to achieve dual-chamber leadless pacing.
Study context
- Population
- Patients with a prior ventricular leadless pacemaker indicated for a dual-chamber pacemakerattempted upgrade
- Participants
- 35 patients
- Outcome
- Upgrade success (single- to dual-chamber leadless pacing)
Main finding
As reported in the abstract
Successful upgrade
Upgrade
91.4%
Observational data: associations, not effects.
Further findings
Atrial device electrical measurements · 12 months
- Capture threshold at 0.4 ms (mean ± SD)
- 0.8 ± 0.6 V
- Sense amplitude (mean ± SD)
- 4.5 ± 2.7 mV
- stabilized within 1 month and remained stable through 12 months
Total estimated battery longevity · evaluated at 12 months
- Ventricular LP
- 11.3 ± 4.2 years
- Atrial LP
- 5.7 ± 2.6 years
- accounting for time since implant
Safety
Complications (all procedure-related) · 12 months
- Patients with complications
- 5 (14.3%)
- Complications
- 7
- Device or procedure-related deaths
- 0
- Atrial LP revision (retrieved and replaced) 10 months after implantation
- 1
Original publication
Upgrading expandable leadless pacemakers from single- to dual-chamber. Europace. Published 24 February 2026. doi:10.1093/europace/euag023
Summarised from the published abstract; every number is checked against it