Heart failure & cardiomyopathies

Urinary sodium to guide diuretic therapy in acute heart failure: results of a national survey

ESC Heart FailPublished nationwide cross-sectional electronic survey

Authors' conclusion

While uNa⁺ monitoring is valued by clinicians, its use in AHF in Spain remains inconsistent across specialties. Addressing implementation barriers through education, protocols, and decision-support tools is critical to a broader adoption of uNa⁺ guided therapy in routine care.

Study context

Population
Clinicians from cardiology, internal medicine, emergency medicine, and nephrology managing acute heart failure (AHF) in Spainphysicians responded · cardiology 138 (33%) · internal medicine 159 (39%) · emergency medicine 78 (19%) · nephrology 38 (9%)
Participants
413 clinicians
Exposure
Cardiology vs internal medicine vs emergency medicine vs nephrology
  • Cardiologyn = 138
  • Internal medicinen = 159
  • Emergency medicinen = 78
  • Nephrologyn = 38
Outcome
Measuring uNa+ during AHF hospitalization

Main finding

As reported in the abstract

Overall, reported measuring uNa+ during AHF hospitalization

70%

Routinely

18%

Observational data: associations, not effects.

Further findings

OutcomeNephrology
Usage by nephrologistsHighest usage
Inpatient90%
Outpatient61%

Outpatient application

Outpatient application
32%

Cut-off to define diuretic resistance

Most frequent cut-off
<50 mmol/l

Therapeutic strategies by specialty

Loop diuretic escalation more frequent in cardiology and emergency medicine; thiazides preferred in internal medicine and nephrology

Perceived clinical usefulness of uNa⁺ monitoring

Considered uNa⁺ monitoring clinically useful
78%

Barriers

Lack of standardized protocols, limited training, therapeutic inertia, and logistical constraints

Original publication

Urinary sodium to guide diuretic therapy in acute heart failure: results of a national survey. ESC Heart Fail. Published 13 January 2026. doi:10.1093/eschf/xvag006

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