Acute cardiac care & resuscitation
Use of Mechanical Circulatory Support in Patients with Non-Ischaemic Cardiogenic Shock
Main findingResult — go to the resultHazard ratio 0.76 95% CI 0.59–0.97Authors' conclusion
In patients with non-ischaemic CS, MCS use was associated with lower 30-day mortality as compared to medical therapy only, but also with more complications.
Study context
- Population
- Patients with non-ischaemic cardiogenic shock (severe de-novo or acute-on-chronic HF, no need for urgent revascularization)386 (43%) with mechanical circulatory support (MCS)
- Participants
- 890 patients
- Exposure
- Active MCS vs no MCS
- MCSn = 267
- No MCSn = 267reference
- Outcome
- Mortality
- Follow-up
- 30 days
Methodological detailsmulticentre, international, propensity-score matched
- Multicentre
- International
- Propensity-score matched
Main finding
As reported in the abstract
Hazard ratio
0.76
95% CI 0.59–0.97
MCSvs No MCS
HR 0.76 (95% CI 0.59–0.97)
Observational data: associations, not effects.
Further findings
30-day mortality by subgroup
- Consistent through all tested subgroups except cardiogenic shock (CS) severity; risk reduction especially in deteriorating CS
Safety
Severe bleeding
Access-site related ischaemia
Original publication
Use of Mechanical Circulatory Support in Patients with Non-Ischaemic Cardiogenic Shock. Eur J Heart Fail. Published 26 February 2023. doi:10.
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