Heart failure & cardiomyopathies
Usefulness of Additional ECG Indicators for Prognosis Prediction in Patients With Cardiac Sarcoidosis
Authors' conclusion
High Tp-e/QT ratios and fQRS presence in CS patients suggest worse prognosis, particularly with LVEF >35%, highlighting their importance in early-stage arrhythmic risk.
Study context
- Population
- Patients with cardiac sarcoidosis, Japanese nationwide survey 2014–2016151 women
- Participants
- 227 patients
- Exposure
- High vs low Tp-e/QT ratio; fQRS present vs absent
- Outcome
- Composite of:
- All-cause mortality
- Ventricular arrhythmia events
- Follow-up
- Median 1,286 days
Methodological detailsmulticentre, Japanese nationwide survey
- Multicentre
- Japanese nationwide survey
Main finding
As reported in the abstract
All-cause mortality and ventricular arrhythmia events
Hazard ratio
3.01
P = 0.002
High Tp-e/QT vs Low Tp-e/QT
Hazard ratio
2.48
P = 0.012
fQRS vs No fQRS
Observational data: associations, not effects.
Secondary outcomes
| Outcome | HR | P value |
|---|---|---|
| Primary outcome, LVEF >35% (subgroup)High Tp-e/QT vs Low Tp-e/QT | 3.62 | P = 0.011 |
| Primary outcome, LVEF >35% (subgroup)fQRS vs No fQRS | 3.38 | P = 0.022 |
Original publication
Usefulness of Additional ECG Indicators for Prognosis Prediction in Patients With Cardiac Sarcoidosis. JACC Clin Electrophysiol. Published 28 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →