Valvular & structural heart disease
Valve Performance Between Latest-Generation Balloon-Expandable and Self-Expandable Transcatheter Heart Valves in a Small Aortic Annulus
Authors' conclusion
In TAVR for SAA, SEV demonstrated better hemodynamics than the latest BEV, whereas the latest BEV had lower incidences of PVL ≥ mild and new PMI than the SEV.
Study context
- Population
- Patients undergoing transcatheter aortic valve replacement (TAVR) for AS with small aortic annulus (annulus area ≤430 mm²)
- Participants
- 1,227 patients
- Exposure
- Latest-generation balloon-expandable valve (BEV) vs self-expandable valve (SEV) for TAVR in small aortic annulus
- BEVn = 798
- Outcome
- Severe prosthesis-patient mismatch, aortic valve mean pressure gradient ≥20 mm Hg, paravalvular leakage (PVL) ≥ mild, new permanent pacemaker implantation and modified VARC-3 device success
- Follow-up
- Discharge
Methodological detailspropensity score analysis, logistic regression
- Propensity score analysis
- Logistic regression
Main finding
As reported in the abstract
- Modified VARC-3 device success comparable between BEV and SEV
- Results confirmed by propensity score analysis
Observational data: associations, not effects.
Safety
| Outcome | OR (95% CI) | |
|---|---|---|
| New permanent pacemaker implantation · discharge | 0.53 (0.33–0.86) | |
| 0.20.5125Odds ratio (log scale) |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Valve Performance Between Latest-Generation Balloon-Expandable and Self-Expandable Transcatheter Heart Valves in a Small Aortic Annulus. JACC Cardiovasc Interv. Published 25 November 2024. doi:10.
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