Arrhythmias & electrophysiology
Variant patterns of electrical activation and recovery in normal human hearts revealed by noninvasive electrocardiographic imaging
Authors' conclusion
Activation and recovery patterns vary profoundly between normal subjects, but are stable individually beat to beat, with a male preponderance to shorter recovery.
Study context
- Population
- Normal human subjects (age 49 ± 14 years, 6/22 male) and subjects with bundle branch block (BBB) or long-QT syndrome (LQTS), assessed by noninvasive ECG imaging (electrocardiographic imaging (ECGI))
- Participants
- 22 / 4 / 4
- Comparison
- Normal subjects vs subjects with BBB or LQTS; Left ventricle (LV) vs right ventricle (RV), sexes, age groups (<50/≥50 years)
- Normaln = 22reference
- BBBn = 4
- LQTSn = 4
- Outcome
- Epicardial activation and recovery patterns by ECGI
Main finding
As reported in the abstract
- Median Pearson correlation coefficient (CC), between-subject: ECG signals
- 0.61
- Median Pearson CC, between-subject: activation patterns
- 0.32
- Median Pearson CC, between-subject: recovery patterns
- 0.19
- CC, within-subject beat-to-beat: ECG signals
- 0.98
- CC, within-subject beat-to-beat: activation patterns
- 0.89
- CC, within-subject beat-to-beat: recovery patterns
- 0.82
Further findings
Activation and/or recovery patterns in BBB or LQTS
- Contrasted significantly with the normal population
Original publication
Variant patterns of electrical activation and recovery in normal human hearts revealed by noninvasive electrocardiographic imaging. Europace. Published 5 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →