Arrhythmias & electrophysiology
Ventricular Duration Map Area as a Valuable and Effective Target for Ventricular Tachycardia (VT) Ablation End Point in Ischemic Cardiomyopathy: The Ventricular Electrogram Duration Map (VEDUM) FREEDOM Study
Authors' conclusion
VEDUM area ablation represented a new target for catheter ablation of VT in patients with ischemic cardiomyopathy.
Study context
- Population
- Patients with ischemic cardiomyopathy undergoing VT ablation
- Participants
- 71 patients
- Exposure
- Extent of VEDUM area ablated
- Outcome
- Any recurrence of sustained VT
- Follow-up
- Mean 24.4±13.9 months
Methodological details2 centres
- 2 centres
Main finding
As reported in the abstract
Arrhythmia-free survival (sustained VT recurrence), by % of VEDUM area ablated
HR for VT recurrence (CI)P value
Ablation of ≥50% of VEDUM area
0.374(0.147–0.947)
P value, 0.038VT inducibility
4.087(1.341–12.450)
P value, 0.013- Primary outcome (any sustained VT recurrence), all patients
- 18 (25.4%)
- Arrhythmia-free survival across VEDUM ablation categories
- log-rank P value: 0.047
Observational data: associations, not effects.
Further findings
VEDUM area characteristics
- Mean VEDUM area size
- 14.6±10.3 cm²
- VEDUM area in a low voltage area
- 65 (91.6%)
- Deceleration zone inside VEDUM area
- 71.8%
- Late potentials inside VEDUM area
- 73.2%
Original publication
Ventricular Duration Map Area as a Valuable and Effective Target for VT Ablation End Point in Ischemic Cardiomyopathy: The VEDUM FREEDOM Study. Circ Arrhythm Electrophysiol. Published 15 October 2025. doi:10.
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