Acute cardiac care & resuscitation

Ventilation Strategies in Cardiogenic Shock: Insights from the AltShock-2 Registry

Eur J Heart FailPublished Prospective registry study

Authors' conclusion

Compared to previous studies, we observed a rising trend in the utilization of NIV among cardiogenic shock patients, irrespective of aetiology and SCAI stages.

Study context

Population
Patients with cardiogenic shock, enrolled March 2020 to November 2023
Participants
657 patients
Exposure
Non-invasive ventilation (NIV) vs invasive mechanical ventilation (iMV) vs oxygen therapy
  • Oxygen therapy (OT)n = 198
  • NIVn = 96
  • iMVn = 363reference
Outcome
All-cause mortality
Follow-up
60 days

Main finding

As reported in the abstract

Hazard ratio

1.97

95% CI 0.85–4.56

By group

NIVvs iMV
HR 1.97 (95% CI 0.85–4.56)
60-day mortality differed across the three groups, even after excluding cardiac arrest at presentation
P = 0.005

Observational data: associations, not effects.

Further findings

All-cause mortality · 24 h

Did not differ amongst the three groups

Original publication

Ventilation Strategies in Cardiogenic Shock: Insights from the AltShock-2 Registry. Eur J Heart Fail. Published 6 August 2024. doi:10.1002/ejhf.3409

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