Arrhythmias & electrophysiology
Visualization of monopolar biphasic focal pulsed field ablation lesions 3 months after pulmonary vein isolation on high-resolution 3-dimensional dark-blood late gadolinium enhancement cardiac magnetic resonance images
Main finding · Image intensity ratio (IIR)Result — go to the resultAverage increase 0.099Authors' conclusion
Left atrial regions that were ablated with monopolar F-PFA have a significantly higher IIR than nonablated regions with 1.08 as the optimal IIR threshold to distinguish between ablated and nonablated regions.
Study context
- Population
- Patients undergoing pulmonary vein isolation (PVI) by monopolar biphasic focal pulsed field ablation (F-PFA) (Centauri, CardioFocus)Three patients were excluded from the analysis
- Participants
- 18 patients
- Comparison
- Image intensity ratio (IIR) between ablated and nonablated regions; IIR threshold to detect ablated regions
- Outcome
- Image intensity ratio (IIR)
- Follow-up
- 3 months after PVI
Methodological detailshigh-resolution 3-dimensional dark-blood late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR) 3 months after PVI, linear mixed-effects model, ROC analyses
- High-resolution 3-dimensional dark-blood LGE CMR 3 months after PVI
- Linear mixed-effects model
- ROC analyses
Main finding
As reported in the abstract
Average increase
0.099
By group
Nonablated region
1.048
median
Further findings
Area under the ROC curve to distinguish between ablated and nonablated regions
- Median area under the ROC curve
- 0.70
Optimal IIR threshold
- Median optimal IIR threshold
- 1.08
Original publication
Visualization of monopolar biphasic focal pulsed field ablation lesions 3 months after pulmonary vein isolation on high-resolution 3-dimensional dark-blood late gadolinium enhancement cardiac magnetic resonance images. Heart Rhythm. Published 5 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →