Heart failure & cardiomyopathies
Accelerometer vs. Other Activity Measures in Heart Failure with Preserved Ejection Fraction: The VITALITY-HFpEF Trial
Authors' conclusion
Accelerometer-based activity measures did not correlate with subjective or objective standard measures of health status and functional capacity in heart failure with preserved ejection fraction.
Study context
- Population
- Patients with HFpEF in the VITALITY-HFpEF accelerometry substudy
- Participants
- 69 patients
- Comparison
- Change in accelerometry activity vs change in Kansas City Cardiomyopathy Questionnaire-Physical Limitation Score (KCCQ-PLS) and 6MWT
- Primary endpoint
- Association between change in accelerometry activity and deterioration, improvement or no change in KCCQ-PLS (≥8.33 and ≤ −4.17 points) and 6MWT (≥32 vs. ≤ −32 m)
- Follow-up
- Baseline to 24 weeks
Methodological detailsaccelerometry substudy
- Accelerometry substudy
Primary result
As reported in the abstract
Change in hours activeOdds ratio (95% CI)P value
KCCQ-PLS deterioration, improvement or no change
0.91(0.71–1.18)
P = 0.486MWT deterioration, improvement or no change
1.21(0.91–1.60)
P = 0.18- KCCQ-PLS deteriorated
- 16
- KCCQ-PLS improved
- 34
- KCCQ-PLS unchanged
- 19
- 6MWT deteriorated
- 8
- 6MWT improved
- 21
- 6MWT unchanged
- 19
Further findings
Other accelerometry metrics vs change in KCCQ and 6MWT
- Similar lack of association
- Unaffected when KCCQ and 6MWT examined as continuous variables
Accelerometer wear
- Mean accelerometer wear, h/day (±2.1)
- 21.4
Original publication
Accelerometer vs. Other Activity Measures in Heart Failure with Preserved Ejection Fraction: The VITALITY-HFpEF Trial. ESC Heart Fail. Published 20 November 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →