Arrhythmias & electrophysiology
Wavefront curvature analysis derived from preprocedural imaging can identify the critical isthmus in patients with postinfarcted ventricular tachycardia
Authors' conclusion
Wavefront curvature measured by ΔT/T and caused by source-sink mismatch is dependent on ventricular wall thickness. Areas of high wavefront curvature partly coincide with and may be helpful in locating the VT isthmus in infarct border zones using preprocedural imaging analysis.
Study context
- Population
- Patients undergoing catheter ablation for postinfarction ventricular tachycardia (VT), with computed tomography (CT) 1–3 days before electrophysiological (EP) study8 VT morphologies
- Participants
- 6 patients
- Comparison
- ΔT/T at lateral isthmus boundaries vs isthmus midline and global left ventricular (LV) mean
- Outcome
- Whether CT-derived LV wall thickness (T) and wavefront curvature (ΔT/T) localize areas of conduction block (VT isthmus)
Main finding
As reported in the abstract
- ΔT/T at boundaries significantly larger than at isthmus midline and than global LV mean
- P <.001
Original publication
Wavefront curvature analysis derived from preprocedural imaging can identify the critical isthmus in patients with postinfarcted ventricular tachycardia. Heart Rhythm. Published 5 June 2024. doi:10.
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