Weight gain after smoking cessation does not modify its protective effect on myocardial infarction and stroke: evidence from a cohort study of men
Authors' conclusion
Post-cessation BMI change did not significantly modify the protective association of smoking cessation with MI and stroke.
Study context
- Population
- Men aged over 40 years without previous myocardial infarction (MI) or stroke, Korean National Health Insurance Service (NHIS) data set 2002–2013
- Participants
- 108,242 men
- Exposure
- Smoking cessation by post-cessation body mass index (BMI) change vs sustained smoking
- Outcome
- MI and stroke
- Follow-up
- 1 January 2006 to 31 December 2013
Main finding
As reported in the abstract
Each group vs sustained smokersHazard ratio (95% CI)
Quitters with BMI gainMI
0.33(0.16–0.70)
Quitters with BMI gainstroke
0.75(0.57–1.00)
Quitters without BMI changeMI
0.55(0.37–0.83)
Quitters without BMI changestroke
0.75(0.62–0.92)
Quitters with BMI lossMI; not significant
0.91(0.43–1.91)
Quitters with BMI lossstroke; not significant
0.86(0.57–1.31)
Non-smokersMI
0.37(0.32–0.43)
Non-smokersstroke
0.68(0.64–0.73)
Observational data: associations, not effects.
Original publication
Weight gain after smoking cessation does not modify its protective effect on myocardial infarction and stroke: evidence from a cohort study of men. Eur Heart J. Published 6 January 2018. doi:10. 1093/ eurheartj/ ehx761
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