Congenital heart disease

Z Scores for Pediatric Echocardiography Dimensions Adjusted for Body Size, BMI, and Age

Circ Cardiovasc ImagingPublished retrospective cross-sectional study

Authors' conclusion

The proposed Z score equations may improve diagnostic and therapeutic accuracy by ensuring that body size, body mass index, and age do not confound the interpretation of measurements.

Study context

Population
Children without heart disease who underwent clinical echocardiography that was reported as normalreference sample of children without heart disease from 9 institutions
Participants
>20,000 children
Exposure
Proposed Z scores compared with a model that only considered body surface area
Outcome
Bias in subgroups of overweight, young, and early school-aged children
Methodological detailsCanadian Congenital and Pediatric Cardiology Research Network, 9 institutions
  • Canadian Congenital and Pediatric Cardiology Research Network
  • 9 institutions

Main finding

As reported in the abstract

  • Proposed Z scores demonstrated less bias than a model that only considered body surface area in subgroups of overweight, young, and early school-aged children

Observational data: associations, not effects.

Original publication

Z Scores for Pediatric Echocardiography Dimensions Adjusted for Body Size, BMI, and Age. Circ Cardiovasc Imaging. Published 9 July 2025. doi:10.1161/circimaging.124.017944

Composed by AI from the published abstract and checked against it. How Briefs are made →

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