Arrhythmias & electrophysiology

A Novel Radiofrequency-Assisted Trans–Right Atrial Appendage (RAA) Perforation Technique for Pericardial CO2 Insufflation to Facilitate Epicardial Access

JACC Clin ElectrophysiolPublished Case series

Authors' conclusion

Intentional RAA perforation for pericardial CO2 insufflation with a custom RF guidewire-microcatheter assembly can be safely and efficiently performed to facilitate epicardial access for ventricular arrhythmias ablation.

Study context

Population
Patients undergoing epicardial access for mapping and ablation of ventricular arrhythmias facilitated by pericardial CO2 insufflation via radiofrequency (RF)-assisted RAA microperforation, 2023–2024age: 55 ± 11 years, left ventricular ejection fraction: 44 ± 13%
Participants
18 patients
Outcome
Successful RAA exit with the RF guidewire-microcatheter assembly

Main finding

As reported in the abstract

  • Achieved in all patients

Observational data: associations, not effects.

Further findings

Epicardial access completed

Patients with epicardial access completed
17 (94%)
Epicardial access deferred because of significant pericardial adhesions detected after RAA exit
1 patient

Time from femoral venous insertion of the catheter assembly to CO2 insufflation

Median time
4 min (range: 3-7 min)

Safety

Significant bleeding (>80 mL)

Patients with significant bleeding
1 patient (patient #3; 150 mL)
  • Led to a modification of the technique (shortening of the RF burst to <1 s with 1-2 mm guidewire exposure past the microcatheter and minimal advancement during RF)

Pericardial bleeding after technique modification (n = 15)

Range
5 mL-30 mL
Median
10 mL
IQR
5-20 mL

Inadvertent right ventricle puncture or damage to a coronary artery

No patient

Pericardial pain after the procedure requiring 1 week of therapy with nonsteroidal anti-inflammatory drugs and colchicine

Patients
Three

Original publication

A Novel Radiofrequency-Assisted Trans–RAA Perforation Technique for Pericardial CO2 Insufflation to Facilitate Epicardial Access. JACC Clin Electrophysiol. Published 12 March 2025. doi:10.1016/j.jacep.2025.01.020

Composed by AI from the published abstract and checked against it. How Briefs are made →

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