Arrhythmias & electrophysiology
A Randomized Trial of Early Endovenous Ablation in Venous Ulceration
Authors' conclusion
Early endovenous ablation of superficial venous reflux resulted in faster healing of venous leg ulcers and more time free from ulcers than deferred endovenous ablation.
Study context
- Population
- Patients with venous leg ulcers
- Participants
- 450 patients
- Comparison
- Early endovenous ablation plus compression vs compression with deferred ablation
- Primary endpoint
- Time to ulcer healing
Methodological detailsmulticentre (20 UK centres)
- Multicentre (20 UK centres)
Primary result
As reported in the abstract
Hazard ratio
1.38
95% CI 1.13–1.68
P = 0.001
By group
Early interventionvs Deferred intervention
HR 1.38 (95% CI 1.13–1.68); P = 0.001
Secondary outcomes
Ulcer healing rate · 24 weeks
Ulcer-free time · first year after enrolment
P = 0.002
Original publication
A Randomized Trial of Early Endovenous Ablation in Venous Ulceration. N Engl J Med. Published 24 April 2018. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →