Heart failure & cardiomyopathies
A Scoring Evaluation for the Practical Introduction of Guideline-Directed Medical Therapy in Heart Failure Patients
Authors' conclusion
The developed simple GDMT score was associated with prognosis in HFrEF and HFmrEF patients.
Study context
- Population
- Patients admitted with HFrEF or heart failure (HF) with mildly reduced EF (HFmrEF), excluding in-hospital death and dialysis
- Participants
- 1,054 patients
- Exposure
- Simple guideline-directed medical therapy (GDMT) score ≥5 vs <5
- Outcome
- All-cause death, HF readmission and composite (HF readmission and all-cause death)
Main finding
As reported in the abstract
All-cause death, HF readmission, composite outcome
- Number of medications not significantly associated with outcomes
- GDMT score ≥5 vs GDMT score <5: P < 0.001
Observational data: associations, not effects.
Further findings
- Almost all subgroups with simple GDMT score ≥5 had a better prognosis
Original publication
A Scoring Evaluation for the Practical Introduction of Guideline-Directed Medical Therapy in Heart Failure Patients. ESC Heart Fail. Published 6 September 2023. doi:10. 1002/ ehf2. 14524
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