Arrhythmias & electrophysiology
UltraSOUND-based characterization of ventricular tachycardia SCAR and arrhythmogenic substrate: The SOUNDSCAR study
Authors' conclusion
ICE-defined scar demonstrates a strong correlation with EAM-defined scar. ICE-guided VT ablation is associated with enhanced procedural efficiency.
Study context
- Population
- Patients with ischemic cardiomyopathy undergoing left ventricular (LV) intracardiac echocardiography (ICE) imaging and electroanatomic mapping (EAM) (SOUNDSCAR cohort)SOUNDSCAR cohort 38
- Participants
- 21 vs 21
- Comparison
- ICE-defined vs EAM-defined scar; ICE-guided vs conventional ventricular tachycardia (VT) ablation
- ICE-guidedn = 21
- Conventionaln = 21reference
- Outcome
- Correlation of ICE-defined scar parameters with EAM-defined scar (voltage <1.5 mV)
Performance
As reported in the abstract
Prediction of EAM-defined scar by ICE parameters (AUC)
- AUC, AHA wall motion score
- 0.873
- AUC, ESWD
- 0.880
- AUC, EDWD
- 0.827
- AUC, slope
- 0.855
- AUC, percentage difference between EDWD and ESWD
- 0.851
- All ICE parameters large effect sizes (logistic regression)
- P < .001
Further findings
Procedure time · separate cohort
P < 0.001
VT recurrence
P = 0.19
Topographical overlap of ICE-defined (slope) and EAM-defined scar
- Overlap
- 88% ± 10%
- Possible in 25 patients
Original publication
UltraSOUND-based characterization of ventricular tachycardia SCAR and arrhythmogenic substrate: The SOUNDSCAR study. Heart Rhythm. Published January 2024. doi:10.
Summarised from the published abstract; every number is checked against it