Arrhythmias & electrophysiology
Accurate detection of lead malfunction from electrocardiogram (ECG)-derived bipolar pacing stimulus amplitude
Authors' conclusion
The maximum amplitude of a bipolar pacing stimulus on the ECG is significantly lower in normal functioning leads compared with those with known malfunction. This simply derived variable demonstrated good accuracy at identifying lead failure due to insulation breach.
Study context
- Population
- Transvenous pacing leads, with known malfunction or normal
- Participants
- 138 transvenous leads
- Comparison
- ECG bipolar pacing stimulus amplitude in malfunctioning vs normal transvenous leads
- Malfunctionn = 88
- Normaln = 50reference
- Outcome
- ECG bipolar stimulus amplitude and diagnostic accuracy for lead malfunction
- Follow-up
- At time of identification of failure
Performance
As reported in the abstract
at time of identification of failure
P < 0.001
- AUC, absolute ECG amplitude
- 0.93 (95% CI 0.891-0.969)
- Sensitivity, cutoff 5 mm/V normalized for output
- 91%
- Specificity, cutoff 5 mm/V normalized for output
- 92%
- AUC, normalized for output
- 0.967 (95% CI 0.938-0.996)
Original publication
Accurate detection of lead malfunction from ECG-derived bipolar pacing stimulus amplitude. Heart Rhythm. Published 2 April 2024. doi:10.
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