Arrhythmias & electrophysiology
Catheter ablation of parahisian premature ventricular complexes in patients with and without cardiac scar
Authors' conclusion
An intramural scar was associated with an intramural SOO of the PVCs requiring more extensive ablation procedures, with similar long-term outcomes compared with those without scar.
Study context
- Population
- Consecutive patients with preprocedure late gadolinium-enhanced cardiac magnetic resonance (LGE-CMR) undergoing ablation of parahisian premature ventricular complexes (PVCs)
- Participants
- 48 patients
- Exposure
- LGE-CMR scar vs no scar
- Scarn = 33
- Outcome
- Incidence and significance of LGE-CMR scarring
Methodological detailsconsecutive patients
- Consecutive patients
Main finding
As reported in the abstract
Intramural LGE-CMR scar
Intramural LGE-CMR scar present
33 of 48
69%
Intramural PVCs, scar vs no scar
64% vs 27%
P < .04
Ablation in multiple chambers, scar vs no scar
58% vs 13%
P < .02
Observational data: associations, not effects.
Further findings
Duration of ablation delivery
P < 0.02
Procedural characteristics, all patients
- Cryoablation used
- 9
- Ablation in multiple chambers required
- 28 (58%)
- PVC site of origin (SOO) intramural
- 25
- PVC SOO LV
- 5
- PVC SOO RV
- 18
- Acute procedural success
- 69%
PVC burden on follow-up
- PVC burden on follow-up (all)
- 6% ± 9%
- Similar with and without scar
Original publication
Catheter ablation of parahisian premature ventricular complexes in patients with and without cardiac scar. Heart Rhythm. Published 2 April 2024. doi:10. 1016/ j. hrthm. 2024. 03. 1813
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