Arrhythmias & electrophysiology

Catheter ablation of parahisian premature ventricular complexes in patients with and without cardiac scar

Heart RhythmPublished Observational cohort study

Authors' conclusion

An intramural scar was associated with an intramural SOO of the PVCs requiring more extensive ablation procedures, with similar long-term outcomes compared with those without scar.

Study context

Population
Consecutive patients with preprocedure late gadolinium-enhanced cardiac magnetic resonance (LGE-CMR) undergoing ablation of parahisian premature ventricular complexes (PVCs)
Participants
48 patients
Exposure
LGE-CMR scar vs no scar
  • Scarn = 33
Outcome
Incidence and significance of LGE-CMR scarring
Methodological detailsconsecutive patients
  • Consecutive patients

Main finding

As reported in the abstract

Intramural LGE-CMR scar

Intramural LGE-CMR scar present

33 of 48

69%

Intramural PVCs, scar vs no scar

64% vs 27%

P < .04

Ablation in multiple chambers, scar vs no scar

58% vs 13%

P < .02

Observational data: associations, not effects.

Further findings

Duration of ablation delivery

P < 0.02

Procedural characteristics, all patients

Cryoablation used
9
Ablation in multiple chambers required
28 (58%)
PVC site of origin (SOO) intramural
25
PVC SOO LV
5
PVC SOO RV
18
Acute procedural success
69%

PVC burden on follow-up

PVC burden on follow-up (all)
6% ± 9%
Similar with and without scar

Original publication

Catheter ablation of parahisian premature ventricular complexes in patients with and without cardiac scar. Heart Rhythm. Published 2 April 2024. doi:10.1016/j.hrthm.2024.03.1813

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