Heart failure & cardiomyopathies
Accurate Fick cardiac output estimation: direct and simultaneous oxygen consumption measurement is imperative in heart failure
Authors' conclusion
In people with severe HF undergoing RHC, VO2 must be directly measured in the HL, rather than on the ward or estimated.
Study context
- Population
- People with severe heart failure (HF) undergoing right heart catheterization (69.6 ± 8.3 years; 74% male)
- Participants
- 80 people
- Exposure
- VO2 measured in the hemodynamic laboratory (HL) vs measured on the ward vs estimated by formulas; Fick cardiac output (CO) vs thermodilution
- Outcome
- VO2
Main finding
As reported in the abstract
- Measured vs estimated VO2 moderate association, r range
- 0.479-0.526
- HL vs ward-measured VO2 agreement moderate, concordance correlation coefficient
- 0.48 (0.31;0.62)
Observational data: associations, not effects.
Further findings
| Outcome | Values |
|---|---|
| CO derived by Fick and by TD | HL-measured 5.03 ± 1.51 L/min · Ward-measured 5.46 ± 1.93 L/min · Bergstra 5.85 ± 1.38 L/min · Dehmer 4.77 ± 1.12 L/min · LaFarge 3.34 ± 0.80 L/min · TD 3.65 ± 1.22 L/min |
- CO derived by Fick and by thermodilution (TD) — CO from HL-measured VO2 vs CO from ward-measured and estimated VO2, r range
- 0.708-0.765
CO derived by Fick and by TD
- CO from HL-measured VO2 differed from all other CO values
Original publication
Accurate Fick cardiac output estimation: direct and simultaneous oxygen consumption measurement is imperative in heart failure. Am Heart J. Published 9 July 2025. doi:10.
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