Aerobic exercise and cardiovascular outcomes in patients with diabetes undergoing percutaneous coronary intervention: a nationwide population-based study
Authors' conclusion
Aerobic exercise maintenance after PCI was associated with a reduced risk of cardiovascular events in patients with diabetes, with a moderate amount of exercise providing maximal benefit.
Study context
- Population
- Patients with DM undergoing Percutaneous Coronary Intervention (PCI), Korean National Health Insurance System
- Participants
- 8,225 patients
- Exposure
- Aerobic exercise habit change before vs after PCI
- Outcome
- Major adverse cardiovascular events (MACE):
- All-cause death
- MI
- Revascularization
- HF
- Follow-up
- Mean 4.9 years
Methodological detailsnationwide population-based, inverse probability-weighted
- Nationwide population-based
- Inverse probability-weighted
Main finding
As reported in the abstract
Each group vs persistent non-exercisersAdjusted hazard ratio (95% CI)
Exercise maintainers
0.78(0.71–0.86)
Exercise discontinuers
0.88(0.79–0.98)
New exercisers
0.89(0.80–1.00)
Observational data: associations, not effects.
Further findings
Amount of aerobic exercise and adverse outcomes
- J-curve relationship; lowest risk at 1000-1499 MET-min/week
- Benefits diminished with ≥1500 MET-min/week
Original publication
Aerobic exercise and cardiovascular outcomes in patients with diabetes undergoing percutaneous coronary intervention: a nationwide population-based study. Eur J Prev Cardiol. Published 24 March 2025. doi:10.
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