Coronary disease & ACS

Risk of Hematologic Malignancies in Patients With Acute Myocardial Infarction: A Nationwide Population-Based Cohort Study

JACC CardioOncolPublished Retrospective cohort study

Authors' conclusion

Patients with AMI had a higher risk of hematologic malignancies than those without AMI.

Study context

Population
Korean National Health Insurance claims database, 2003–2021matched cohort
Participants
103,686 vs 103,686
Exposure
Acute myocardial infarction (AMI) vs no AMI
  • AMIn = 103,686
  • Controln = 103,686reference
Outcome
Incident hematologic malignancies
Methodological detailsage- and sex-matched, competing risk analysis
  • Age- and sex-matched
  • Competing risk analysis

Main finding

As reported in the abstract

Hazard ratio

1.49

95% CI 1.31–1.69

Events by group

AMI

1,043

events

Control

1,479

events

AMIvs Control
HR 1.49 (95% CI 1.31–1.69)

Observational data: associations, not effects.

Further findings

Sensitivity and standardized incidence ratio analyses

Findings consistent

Original publication

Risk of Hematologic Malignancies in Patients With Acute Myocardial Infarction: A Nationwide Population-Based Cohort Study. JACC CardioOncol. Published 27 May 2025. doi:10.1016/j.jaccao.2025.04.003

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