Age- and Sex-Specific Myocardial Blood Flow Values in Patients Without Coronary Atherosclerosis on Rb-82 PET Myocardial Perfusion Imaging
Authors' conclusion
In patients without demonstrable coronary artery disease, MBFR is higher in younger males than younger females and decreases with age in both sexes.
Study context
- Population
- Patients without demonstrable CAD undergoing PET myocardial perfusion imaging, 2012–2022 (summed stress score 0, coronary calcium score 0, LVEF ≥50%; excluding known CAD, prior coronary intervention, DM, heart/kidney/liver transplant, cirrhosis, CKD stage IV+)76.4% females
- Participants
- 2,789 patients
- Exposure
- Males vs females, by age
- Outcome
- Effect of age and sex on MBF and MBFR
Methodological detailsquantile regression
- Quantile regression
Main finding
As reported in the abstract
- Median rest myocardial blood flow (MBF), mL/min·g (IQR not labelled)
- 0.73 (0.60-0.91)
- Median stress MBF, mL/min·g
- 1.72 (1.41-2.10)
- Median myocardial blood flow reserve (MBFR)
- 2.31 (1.96-2.74)
- Predicted MBFR, 20-year-old male
- 3.18
- Predicted MBFR, 20-year-old female
- 2.50
- Predicted MBFR, 80-year-old male
- 2.17
- Predicted MBFR, 80-year-old female
- 2.02
Observational data: associations, not effects.
Original publication
Age- and Sex-Specific Myocardial Blood Flow Values in Patients Without Coronary Atherosclerosis on Rb-82 PET Myocardial Perfusion Imaging. Circ Cardiovasc Imaging. Published 16 July 2024. doi:10.
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