Arrhythmias & electrophysiology
Anatomic, histologic, and mechanical features of the right atrium: implications for leadless atrial pacemaker implantation
Authors' conclusion
Based on anatomical review and 3D modelling, the best compromise for an atrial LP implantation may be the RAA base (low incidence of collision, relatively thick myocardial tissue, and without proximity to relevant epicardial structures); the anteromedial recess of the RAA apex and lateral wall are alternate sites.
Study context
- Population
- Formalin-preserved human hearts and cardiac magnetic resonance imaging (MRI) scans45 hearts
- Comparison
- Candidate right atrial (RA) sites for atrial leadless pacemaker implantation
- Outcome
- Optimal safest location to implant an atrial LP (RA wall thickness, anatomic relationships, mechanical device interaction)
Methodological detailsgross anatomy, cardiac MRI, 3D collision modelling
- Gross anatomy
- Cardiac MRI
- 3D collision modelling
Main finding
As reported in the abstract
| Group | Value | Collision | Adjacent structures |
|---|---|---|---|
| Right atrial appendage (RAA) base | 2.7 ± 1.6 mm | low incidence in virtual implants | |
| RAA apex | 1.3 ± 0.4 mm | minimal interaction | |
| RA lateral wall | 2.6 ± 0.9 mm | close proximity to phrenic nerve and sinoatrial artery |
Value
Right atrial appendage (RAA) base2.7 ± 1.6 mm
RAA apex1.3 ± 0.4 mm
RA lateral wall2.6 ± 0.9 mm
Collision
Right atrial appendage (RAA) baselow incidence in virtual implants
RAA apexminimal interaction
RA lateral wall— not stated in the abstract
Adjacent structures
Right atrial appendage (RAA) base— not stated in the abstract
RAA apex— not stated in the abstract
RA lateral wallclose proximity to phrenic nerve and sinoatrial artery
Original publication
Anatomic, histologic, and mechanical features of the right atrium: implications for leadless atrial pacemaker implantation. Europace. Published 31 July 2023. doi:10. 1093/ europace/ euad235
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