Arrhythmias & electrophysiology

Anatomic, histologic, and mechanical features of the right atrium: implications for leadless atrial pacemaker implantation

EuropacePublished Mechanistic study

Authors' conclusion

Based on anatomical review and 3D modelling, the best compromise for an atrial LP implantation may be the RAA base (low incidence of collision, relatively thick myocardial tissue, and without proximity to relevant epicardial structures); the anteromedial recess of the RAA apex and lateral wall are alternate sites.

Study context

Population
Formalin-preserved human hearts and cardiac magnetic resonance imaging (MRI) scans45 hearts
Comparison
Candidate right atrial (RA) sites for atrial leadless pacemaker implantation
Outcome
Optimal safest location to implant an atrial LP (RA wall thickness, anatomic relationships, mechanical device interaction)
Methodological detailsgross anatomy, cardiac MRI, 3D collision modelling
  • Gross anatomy
  • Cardiac MRI
  • 3D collision modelling

Main finding

As reported in the abstract

GroupValueCollisionAdjacent structures
Right atrial appendage (RAA) base2.7 ± 1.6 mmlow incidence in virtual implants
RAA apex1.3 ± 0.4 mmminimal interaction
RA lateral wall2.6 ± 0.9 mmclose proximity to phrenic nerve and sinoatrial artery

Value

Right atrial appendage (RAA) base2.7 ± 1.6 mm
RAA apex1.3 ± 0.4 mm
RA lateral wall2.6 ± 0.9 mm

Collision

Right atrial appendage (RAA) baselow incidence in virtual implants
RAA apexminimal interaction
RA lateral wall— not stated in the abstract

Adjacent structures

Right atrial appendage (RAA) base— not stated in the abstract
RAA apex— not stated in the abstract
RA lateral wallclose proximity to phrenic nerve and sinoatrial artery

Original publication

Anatomic, histologic, and mechanical features of the right atrium: implications for leadless atrial pacemaker implantation. Europace. Published 31 July 2023. doi:10.1093/europace/euad235

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