Arrhythmias & electrophysiology
Atrial Leadless Pacemaker Implantation at the Superior Right Atrial Site
Authors' conclusion
Superior RA pacing was feasible, showed a marked learning curve, and better preserved intrinsic atrial activation than RAA pacing.
Study context
- Population
- Patients undergoing dual-chamber leadless pacemaker implantation
- Participants
- 68 consecutive patients
- Comparison
- Superior right atrium (RA) vs right atrial appendage (RAA) base pacing
- Outcome
- Superior RA implantation success
Main finding
As reported in the abstract
Successful attempts
26/46 attempts
56.5%
Across sequential periods
from 27.8% to 60.0% and 92.3%
Further findings
Procedure time (noncrossover cases) · noncrossover cases
P = 0.533
Fluoroscopy time (noncrossover cases) · noncrossover cases
P = 0.249
Sensing amplitude · 3 months
P = 0.091
Pacing threshold · 3 months
P = 0.785
| Outcome | Superior RA pacing | RAA base pacing | P value |
|---|---|---|---|
| P-wave duration | mean±SD, before to after 99.7±29.9 to 98.1±25.6 ms | mean±SD, before to after 106.7±23.1 to 134.9±25.6 ms | |
| P | P=0.543 | P<0.001 | |
| P-wave terminal force in V1 | 3.6% to 3.6% | 10.0% to 45.0% | |
| P | — not stated in the abstract | P<0.001 for RAA | |
| PR interval+5.7±11.7 vs +38.6±31.3 ms | mean±SD, before to after 228.4±72.8 to 229.7±77.5 ms | mean±SD, before to after 205.5±72.0 to 234.4±72.6 ms | P < 0.001 |
| P | P=0.038 | P<0.001 | |
| Change | +5.7±11.7 | +38.6±31.3 |
— not stated in the abstract
Mortality, heart failure events, and atrial fibrillation incidence · 10.4±4.6 months
- Did not differ significantly
Safety
- No pericardial tamponade occurred
Original publication
Atrial Leadless Pacemaker Implantation at the Superior Right Atrial Site. Heart Rhythm. Published 30 October 2026. doi:10. 1016/ j. hrthm. 2026. 10. 058
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