Arrhythmias & electrophysiology

Atrial Leadless Pacemaker Implantation at the Superior Right Atrial Site

Heart RhythmPublished Consecutive patients undergoing dual-chamber leadless pacemaker implantation

Authors' conclusion

Superior RA pacing was feasible, showed a marked learning curve, and better preserved intrinsic atrial activation than RAA pacing.

Study context

Population
Patients undergoing dual-chamber leadless pacemaker implantation
Participants
68 consecutive patients
Comparison
Superior right atrium (RA) vs right atrial appendage (RAA) base pacing
Outcome
Superior RA implantation success

Main finding

As reported in the abstract

Successful attempts

26/46 attempts

56.5%

Across sequential periods

from 27.8% to 60.0% and 92.3%

Further findings

Procedure time (noncrossover cases) · noncrossover cases

P = 0.533

Fluoroscopy time (noncrossover cases) · noncrossover cases

P = 0.249

Sensing amplitude · 3 months

P = 0.091

Pacing threshold · 3 months

P = 0.785

OutcomeSuperior RA pacingRAA base pacingP value
P-wave durationmean±SD, before to after 99.7±29.9 to 98.1±25.6 msmean±SD, before to after 106.7±23.1 to 134.9±25.6 ms
PP=0.543P<0.001
P-wave terminal force in V13.6% to 3.6%10.0% to 45.0%
P— not stated in the abstractP<0.001 for RAA
PR interval+5.7±11.7 vs +38.6±31.3 msmean±SD, before to after 228.4±72.8 to 229.7±77.5 msmean±SD, before to after 205.5±72.0 to 234.4±72.6 msP < 0.001
PP=0.038P<0.001
Change+5.7±11.7+38.6±31.3

— not stated in the abstract

Mortality, heart failure events, and atrial fibrillation incidence · 10.4±4.6 months

Did not differ significantly

Safety

No pericardial tamponade occurred

Original publication

Atrial Leadless Pacemaker Implantation at the Superior Right Atrial Site. Heart Rhythm. Published 30 October 2026. doi:10.1016/j.hrthm.2026.10.058

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