Pulmonary vascular disease & thromboembolism

Angiographic Classification of Total Occlusion and Its Implication on Balloon Pulmonary Angioplasty

ESC Heart FailPublished Retrospective cohort study

Corrected 23 Oct 2026: Measure wording clarified; no values changed.

Authors' conclusion

Occlusion morphology has a significant impact on BPA success and complication rates.

Study context

Population
Patients with chronic thromboembolic pulmonary hypertension (CTEPH) undergoing balloon pulmonary angioplasty (BPA) with total occlusion, Fuwai Hospital, Beijing, May 2018–May 202238 occluded lesions in 33 patients
Participants
204 patients
Exposure
Pointed-head vs round-head vs orifice total occlusion in BPA
Outcome
BPA success by occlusion morphology
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

BPA success rate
Each group vs pointed-headOdds ratio (95% CI)P value
Round-head
24.500 (2.498–240.318), event not clearly stated
P = 0.006
Orifice
42.000 (3.034–581.434), event not clearly stated
P = 0.005

Observational data: associations, not effects.

Safety

Complication rate — Orifice
50%
Complication rate — Orifice occlusion had the highest complication rate
50%

Original publication

Angiographic Classification of Total Occlusion and Its Implication on Balloon Pulmonary Angioplasty. ESC Heart Fail. Published 21 December 2023. doi:10.1002/ehf2.14609

Composed by AI from the published abstract and checked against it. How Briefs are made →

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