Valvular & structural heart disease
Annular remodelling predicts outcome in isolated severe tricuspid regurgitation: a registry-based echocardiographic analysis
Authors' conclusion
Severe isolated TR in the absence of AF is a rare finding with a grim prognosis. Tricuspid annular diameter dimensions rather than quantitative measures of TR proved to be of significant prognostic value indicating a continuous remodelling leading to a 'point of no return' with a dismal outcome.
Study context
- Population
- Patients with isolated severe secondary tricuspid regurgitation (vena contracta (VC) ≥ 7 mm) without AF, other valve disease or reduced LV systolic function, tertiary-centre echocardiographic database36,000 screened
- Participants
- 216 patients
- Outcome
- All-cause mortality
- Follow-up
- Median 35 months (20-53)
Methodological detailssingle-centre, registry-based, echocardiographic re-read
- Single-centre
- Registry-based
- Echocardiographic re-read
Main finding
As reported in the abstract
- All-cause mortality
- 31% (n = 67)
- Indexed right ventricular (RV) end-diastolic diameter associated with outcome
- P < 0.001
- Indexed right atrial dimensions associated with outcome
- P = 0.019
- Tricuspid valve (TV) annulus diameter diastole index associated with outcome
- P = 0.002
- TV annulus diameter systole index associated with outcome
- P = 0.001
Observational data: associations, not effects.
Further findings
TR grade distribution
- Massive TR
- n = 23 (10%)
- Torrential TR
- n = 4 (2%)
- Severe TR predominant
Original publication
Annular remodelling predicts outcome in isolated severe tricuspid regurgitation: a registry-based echocardiographic analysis. Eur Heart J Cardiovasc Imaging. Published 10 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →