Arrhythmias & electrophysiology
Antitachycardia pacing success in implantable cardioverter-defibrillators by patient, device, and programming characteristics
Authors' conclusion
Delivering more ATP sequences resulted in a higher overall success of terminating VTs, while programming more ATP was associated with decreased shock burden and no evidence of increased syncope or acceleration.
Study context
- Population
- Patients with implantable cardioverter-defibrillator (ICD) or CRT-D; spontaneous antitachycardia pacing (ATP)-treated monomorphic VT episodes
- Participants
- 2,770 patients
- Comparison
- ATP success by patient, device and programming characteristics
- ICDn = 1,699
- CRT-Dn = 1,071
- Primary endpoint
- ATP success rate for terminating VT
Methodological detailsretrospective
- Retrospective
Primary result
As reported in the abstract
ATP success
P = 0.81
- ATP success for terminating ventricular tachycardias (VTs) overall
- >80%
- Cumulative ATP success at 1 sequence
- 71%
- Cumulative ATP success at ≥8 sequences
- 87%
- ATP success, median cycle length ≥320 ms (significantly higher)
- 88.0% (95% CI 84.8%-90.6%)
Further findings
ATP success, primary vs secondary prevention (ICD)
P = 0.25
Shock burden
- More ATP sequences programmed associated with lower shock burden
- P = 0.0005
Safety
- No evidence more sequences associated with higher syncope
- P = 0.16
Original publication
Antitachycardia pacing success in implantable cardioverter-defibrillators by patient, device, and programming characteristics. Heart Rhythm. Published 19 October 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →