Hypertension

Applying the 2024 European Society of Cardiology Guidelines for the management of elevated blood pressure and hypertension to a Norwegian general population cohort from age 40: data from the Akershus Cardiac Examination 1950 study

HeartPublished Prospective cohort study

Authors' conclusion

A single BP measurement at age 40 identified eBP (130-139/80-89 mm Hg) among one-third of the individuals, yet MACE cases within the eBP category occurred primarily in individuals who were not eligible for medical treatment.

Study context

Population
Norwegian general population born in 1950 (Age 40 Programme and ACE 1950 Study), BP at age 40 and 62–65, linked to national health registries
Participants
2,688 participants
Outcome
Treatment eligibility under the 2024 European Society of Cardiology (ESC) hypertension guidelines and MACE rates in those with eBP (130-139/80-89 mm Hg)
Follow-up
30 years
Methodological detailsregistry-linked, general population cohort
  • Registry-linked
  • General population cohort

Main finding

As reported in the abstract

Elevated BP (eBP) (130-139/80-89 mm Hg) at age 40
854 (32%) of 2688
eBP at age 40 with elevated cardiovascular (CV) risk warranting pharmacological treatment
4
On BP-lowering medication or BP ≥140/90 at age 62-65
1657 (61%)
eBP at age 62-65 eligible for drug treatment
64 (8%) out of 851
Major adverse cardiovascular events (MACEs) in eBP category (BP at age 40) among those eligible for pharmacological treatment
2 of the 93

Observational data: associations, not effects.

Original publication

Applying the 2024 European Society of Cardiology Guidelines for the management of elevated blood pressure and hypertension to a Norwegian general population cohort from age 40: data from the Akershus Cardiac Examination 1950 study. Heart. Published 22 May 2025. doi:10.1136/heartjnl-2025-325770

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