Heart failure & cardiomyopathies
Are non-invasive estimations of plasma volume an accurate measure of congestion in patients with chronic heart failure?
Authors' conclusion
Amongst patients with CHF, HPVS and DPVS are not strongly or consistently associated with clinical or ultrasound evidence of congestion, nor clinical outcomes after multivariable adjustment.
Study context
- Population
- Patients with chronic heart failure (HF) in the Hull Lifelab registrycohort 1 n = 3505
- Exposure
- Hakim vs Duarte formulae for estimated plasma volume status vs clinical and ultrasound markers of congestion
- Outcome
- Associations of PVS with congestion and outcomes
Main finding
As reported in the abstract
Estimate (95% CI)P value
HPVSmortality, cohort 1
HR per unitary increase 1.02(1.01–1.03)
P < 0.001HPVSB-line count, cohort 2
HR 1.05(1.01–1.08)
P = 0.02DPVSHF hospitalisation or all-cause mortality, cohort 2
HR 1.26(1.01–1.58)
P = 0.04Observational data: associations, not effects.
Original publication
Are non-invasive estimations of plasma volume an accurate measure of congestion in patients with chronic heart failure? Eur Heart J Qual Care Clin Outcomes. Published 20 June 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →