Valvular & structural heart disease
Arrhythmia Occurrence After Balloon-Expandable and Self-Expanding Transcatheter Pulmonary Valve Replacement
Authors' conclusion
Arrhythmias are common after TPVR beyond the early postimplantation period. No statistical difference could be determined for incidence of life-threatening arrhythmia or mortality between BEPVR or SEPVR. NSVT was the most observed arrhythmia and occurred significantly more often after SEPVR, independent of preimplantation arrhythmia history. Longer term studies are needed to determine the prognostic implication of NSVT after TPVR and the potential relationship to late life-threatening arrhythmias or mortality.
Study context
- Population
- Patients undergoing transcatheter pulmonary valve replacement (TPVR) at the authors' institution from 2012 to 2022 with rhythm monitoring beyond 14 days' postprocedurepatients, mean age 40.6 ± 16.4 years, median (IQR) follow-up 4.0 (5.5) years
- Participants
- 68 patients
- Comparison
- BEPVR vs SEPVR
- BEPVRn = 49
- SEPVRn = 19
- Outcome
- Composite of:
- All-cause mortality
- Life-threatening arrhythmia
Methodological detailssingle institution
- Single institution
Secondary outcomes
- Nonsustained ventricular tachycardia (NSVT) — Patients with NSVT (most frequent non-life-threatening arrhythmia) · significantly more common after SEPVR
- 47.1% · P = 0.03
Life-threatening arrhythmias
- Patients with life-threatening arrhythmias
- 13 patients (19.1%)
- All but one following BEPVR
NSVT
- NSVT persisted beyond the early postprocedural period but was not associated with life-threatening arrhythmias or mortality
Diagnoses
- Tetralogy of Fallot
- 45.6%
- Congenital pulmonary valve stenosis
- 23.5%
- Bicuspid aortic valve status-post Ross procedure
- 14.7%
- Acquired pulmonary valve disease
- 7.4%
- Procedure type: BEPVR 49 patients (72.1%)
- SEPVR was performed in 19 patients (27.9%)
Original publication
Arrhythmia Occurrence After Balloon-Expandable and Self-Expanding Transcatheter Pulmonary Valve Replacement. JACC Clin Electrophysiol. Published March 2026. doi:10.
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