Arrhythmias & electrophysiology

Artificial Intelligence–Based Feature Analysis of Pulmonary Vein Morphology on Computed Tomography Scans and Risk of Atrial Fibrillation Recurrence After Catheter Ablation: A Multi-Site Study

Circ Arrhythm ElectrophysiolPublished Prognostic model development and validation study

Authors' conclusion

This largest multi-institutional study to date revealed associations between artificial intelligence-extracted morphological features of the primary PV branches with AF recurrence in 809 patients from 3 sites.

Study context

Population
Patients undergoing catheter ablation of atrial fibrillation (AF) with CT imaging (Cleveland Clinic, Vanderbilt University, University Hospitals of Cleveland)
Participants
809 patients3 sites
Comparison
AI-derived radiomic features of primary vs secondary vs combined pulmonary vein (PV) branches for predicting AF recurrence
Outcome
AF recurrence after catheter ablation
Methodological detailsmulti-site, 3 sites, AI-based CT segmentation, independent validation set, 48 fractal-based and 12 shape-based radiomic features extracted from primary and secondary PV branches
  • Multi-site
  • 3 sites
  • AI-based CT segmentation
  • Independent validation set
  • 48 fractal-based and 12 shape-based radiomic features extracted from primary and secondary PV branches

Performance

As reported in the abstract

AF recurrence prediction
Test or modelAUC D1AUC D2AUC D3
Mp0.730.710.70

Mp

AUC D10.73
AUC D20.71
AUC D30.70

Original publication

Artificial Intelligence–Based Feature Analysis of Pulmonary Vein Morphology on Computed Tomography Scans and Risk of Atrial Fibrillation Recurrence After Catheter Ablation: A Multi-Site Study. Circ Arrhythm Electrophysiol. Published 3 December 2024. doi:10.1161/circep.123.012679

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