Acute cardiac care & resuscitation

Association between air pollutants and out-of-hospital cardiac arrest: a 5-year time series analysis

Eur Heart J Acute Cardiovasc CarePublished time series analysis

Main finding · OHCA per 10 μg/m³ increase in PM2.5Result — go to the resultRelative risk 1.026 95% CI 1.001–1.053

Authors' conclusion

Improving the levels of PM2.5, NO2, and O3 could decrease the risk of OHCA and the demand for emergency medical service related to PM2.5 exposure.

Study context

Population
Out-of-hospital cardiac arrest (OHCA) events reported to the Shenzhen Emergency Center, Shenzhen, Chinapatients who experienced OHCA
Participants
16,769 participants
Comparison
Association among PM2.5, O3, PM10, CO, NO2, SO2 and OHCA
Outcome
OHCA per 10 μg/m³ increase in PM2.5
Follow-up
Lag Day 1
Methodological details5-year
  • 5-year

Main finding

As reported in the abstract

Relative risk

1.026

95% CI 1.001–1.053

10 μg/m³ increase in PM2.5
RR 1.026 (95% CI 1.001–1.053)

Per 10 μg/m³ increase in PM2.5, as printed

Further findings

OutcomeRR (95% CI)
OHCA per 10 μg/m³ increase in PM10, onset dayImmediate risk1.02 (1.005–1.036)
OHCA per 10 μg/m³ increase in PM10, cumulative · lag Day 1Cumulative risk1.021 (1.003–1.039)

OHCA with NO2, O3, SO2 and CO exposure · subsequent 5 days

An increased risk of OHCA was associated with NO2 and O3 exposure
A reduced risk of OHCA was associated with SO2 and CO exposure

PM2.5 and OHCA by gender and arrest rhythm (subgroup)

The relationship between PM2.5 and OHCA varied by gender and arrest rhythm

Decrease in OHCA incidence attributable to PM2.5 exposure · lag Day 1

Reduction in average daily PM2.5 by 1 µg/m³
4.60%
Reduction in average daily PM2.5 by 3 µg/m³
18.41%

Original publication

Association between air pollutants and out-of-hospital cardiac arrest: a 5-year time series analysis. Eur Heart J Acute Cardiovasc Care. Published 23 January 2025. doi:10.1093/ehjacc/zuaf013

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