Cardio-oncology & otherMeta-analysis
Association between cardiovascular disease and risk of female sexual dysfunction: a systematic review and meta-analysis
- Systematic review and meta-analysis of observational studies
- random-effects models
- Newcastle-Ottawa Scale quality assessment
- Databases searched from inception to 28 February 2023
Authors' conclusion
Our meta-analysis indicated that patients with CVD suffer from a greater risk of developing FSD.
Study context
- Population
- Women with or without cardiovascular diseases (CVD); studies reporting the risk of female sexual dysfunction (FSD)54 articles
- Participants
- 148,946 women
- Comparison
- CVD vs no CVD
- Outcome
- Female sexual dysfunction (FSD)
Pooled result
FSD
Odds ratio
1.51
95% CI 1.34–1.69
P < 0.001
CVD vs Control
OR 1.51 (95% CI 1.34–1.69); P < 0.001
As reported in the abstract
Further pooled results
| Outcome | Estimate | P value | |
|---|---|---|---|
| FSD, longitudinal studies (subgroup) · heterogeneity I2 = 86.7%, P < 0.001 | RR 1.50 (95% CI 1.21–1.86) | P < 0.001 | |
| FSD by condition: hypertension, stroke, myocardial infarction — hypertension vs Control · heterogeneity I2 = 82.7%, P < 0.001 | OR 1.41 (95% CI 1.23–1.62) | P < 0.001 | |
| FSD by condition: hypertension, stroke, myocardial infarction — stroke vs Control · heterogeneity I2 = 0%, P < 0.423 | OR 1.81 (95% CI 1.54–2.12) | P < 0.001 | |
| FSD by condition: hypertension, stroke, myocardial infarction — myocardial infarction vs Control · heterogeneity I2 = 82.4%, P < 0.001 | OR 2.07 (95% CI 1.60–2.67) | P < 0.001 | |
| 0.20.5125Ratio (log scale) |
Sources of heterogeneity (meta-regression)
- Primary sources of heterogeneity attributable to adjustments for covariates, study design and study population
Original publication
Association between cardiovascular disease and risk of female sexual dysfunction: a systematic review and meta-analysis. Eur J Prev Cardiol. Published 31 January 2024. doi:10.1093/eurjpc/zwae042
Summarised from the published abstract; every number is checked against it