Heart failure & cardiomyopathies
Association Between Caseload Volume and Outcomes in Left Ventricular Assist Device Implantations – a EUROMACS Analysis
Authors' conclusion
In patients undergoing LVAD implantation, centre volume was not associated with 1-year survival, but was related to device-related adverse events. Patient profiles differed with respect to centre size.
Study context
- Population
- Patients undergoing left ventricular assist device (LVAD) implantation, EUROMACS registry, 35 centres, 2011–2020
- Participants
- 4,802 patients35 centres
- Exposure
- Higher-volume vs lower-volume centres
- Outcome
- 1-year survival
- Follow-up
- 1 year
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Adjusted 1-year survival
- No difference in adjusted 1-year survival
Observational data: associations, not effects.
Secondary outcomes
| Outcome | Adjusted OR (95% CI) | P value | |
|---|---|---|---|
| 1-year survival, HeartMate 3 devices only (subgroup) | 0.43 (0.20–0.97) | P = 0.041 | |
| 0.20.5125Adjusted odds ratio (log scale) |
Adjusted overall survival
- Adjusted overall survival probability lower in higher volume centres
- P = 0.002
- Median follow-up 1.54 years (IQR 0.52-3.15)
Cumulative (learning curve) caseload analyses
- Similar findings observed
Original publication
Association Between Caseload Volume and Outcomes in Left Ventricular Assist Device Implantations – a EUROMACS Analysis. Eur J Heart Fail. Published 29 August 2024. doi:10.
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