Heart failure & cardiomyopathies

Association Between Lactate/Albumin Ratio and Mortality in Patients with Heart Failure After Myocardial Infarction

ESC Heart FailPublished Retrospective cohort study

Authors' conclusion

Elevated L/A ratio on admission is an independent predictor of high in-hospital mortality in post-MI heart failure patients, which proved to be better than lactate, Sequential Organ Failure Assessment score and other related indicators.

Study context

Population
Patients with heart failure (HF) after myocardial infarction (MI), MIMIC-IV database
Exposure
High vs low L/A ratio on admission
Outcome
In-hospital mortality

Main finding

As reported in the abstract

Increasing, non-linear relationship between L/A and in-hospital mortality (restricted cubic splines (RCS))

<0.05

AUC of admission L/A for in-hospital mortality

0.780

95% CI 0.772–0.827

Best cut-off value of L/A

0.671

Observational data: associations, not effects.

Further findings

OutcomeDeathSurvivalP value
Admission L/A value, death vs survival1.36 (not stated 1.20)0.62 (not stated 0.36)P < 0.05

Original publication

Association Between Lactate/Albumin Ratio and Mortality in Patients with Heart Failure After Myocardial Infarction. ESC Heart Fail. Published 28 March 2023. doi:10.1002/ehf2.14359

Composed by AI from the published abstract and checked against it. How Briefs are made →

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