Heart failure & cardiomyopathies

Association between Life’s Essential 8 and risk of heart failure: findings from the Kailuan study

Eur J Prev CardiolPublished Prospective cohort study

Main finding · HFResult — go to the resultHazard ratio 0.43 95% CI 0.34–0.55

Authors' conclusion

LE8 was inversely associated with HF risk. Individuals with initially low LE8 levels experienced a reversal in HF risk upon improvement.

Study context

Population
Adults without prior heart failure (HF), Kailuan community461 HF events
Participants
35,896 adults
Exposure
LE8 trajectories, status and annual change rate and risk of HF
Outcome
Incident HF

Main finding

HF

Hazard ratio

0.43

95% CI 0.34–0.55

Moderate-increasingvs Moderate-decreasing
HR 0.43 (95% CI 0.34–0.55)

As reported in the abstract

Observational data: associations, not effects.

Further findings

Prediction of HF (C-index)

LE8 trajectory more accurate than LE8 status in predicting HF risk

Original publication

Association between Life’s Essential 8 and risk of heart failure: findings from the Kailuan study. Eur J Prev Cardiol. Published 5 February 2025. doi:10.1093/eurjpc/zwaf024

Composed by AI from the published abstract and checked against it. How Briefs are made →

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