Acute cardiac care & resuscitation
Association between postresuscitation 12-lead ECG features and long-term neurological outcome after out-of-hospital cardiac arrest: a post-hoc subanalysis of the PEACE study
Authors' conclusion
ECG after ROSC can identify patients at high risk of death after OHCA earlier than other prognostic methods, not only in terms of short-term mortality, but also in terms of neurological outcome one year after OHCA. Wider QRS complex and ST-elevations in II, III, or aVF were identified as specific prognosticators.
Study context
- Population
- Adult non-traumatic out-of-hospital cardiac arrest (OHCA) cases with post-ROSC ECGs admitted to one of three centers in Vienna (Austria), Pavia (Italy) and Lugano (Switzerland) between 01/2015 and 12/2018
- Exposure
- Associations between ECG features and neurological outcome
- Outcome
- STEMI on post-ROSC ECG
Methodological detailspost-hoc subanalysis, three participating centers
- Post-hoc subanalysis
- Three participating centers
Main finding
As reported in the abstract
STEMI diagnosed in post-ROSC ECGs
53.5%
Observational data: associations, not effects.
Further findings
Favorable neurological outcome · one year
Discharged from hospital; favorable neurological outcome · hospital discharge
- Patients discharged
- 68.1%
- Favorable neurological outcome
- 59.5%
ECG features and neurological outcome · one year
- ST-elevations in II, III, and aVF, as well as a broader QRS complex significantly influenced neurological outcomes at one year
- Univariable analysis
Original publication
Association between postresuscitation 12-lead ECG features and long-term neurological outcome after out-of-hospital cardiac arrest: a post-hoc subanalysis of the PEACE study. Resuscitation. Published 5 May 2025. doi:10. 1016/ j. resuscitation. 2025. 110630
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