Acute cardiac care & resuscitation

Association between postresuscitation 12-lead ECG features and long-term neurological outcome after out-of-hospital cardiac arrest: a post-hoc subanalysis of the PEACE study

ResuscitationPublished retrospective study

Authors' conclusion

ECG after ROSC can identify patients at high risk of death after OHCA earlier than other prognostic methods, not only in terms of short-term mortality, but also in terms of neurological outcome one year after OHCA. Wider QRS complex and ST-elevations in II, III, or aVF were identified as specific prognosticators.

Study context

Population
Adult non-traumatic out-of-hospital cardiac arrest (OHCA) cases with post-ROSC ECGs admitted to one of three centers in Vienna (Austria), Pavia (Italy) and Lugano (Switzerland) between 01/2015 and 12/2018
Exposure
Associations between ECG features and neurological outcome
Outcome
STEMI on post-ROSC ECG
Methodological detailspost-hoc subanalysis, three participating centers
  • Post-hoc subanalysis
  • Three participating centers

Main finding

As reported in the abstract

STEMI diagnosed in post-ROSC ECGs

53.5%

Observational data: associations, not effects.

Further findings

Favorable neurological outcome · one year

Discharged from hospital; favorable neurological outcome · hospital discharge

Patients discharged
68.1%
Favorable neurological outcome
59.5%

ECG features and neurological outcome · one year

ST-elevations in II, III, and aVF, as well as a broader QRS complex significantly influenced neurological outcomes at one year
  • Univariable analysis

Original publication

Association between postresuscitation 12-lead ECG features and long-term neurological outcome after out-of-hospital cardiac arrest: a post-hoc subanalysis of the PEACE study. Resuscitation. Published 5 May 2025. doi:10.1016/j.resuscitation.2025.110630

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