Arrhythmias & electrophysiology
Association Between Right Bundle Branch Block and Ventricular Arrhythmia in Patients With Cardiac Sarcoidosis
Primary resultResult — go to the resultHazard ratio 1.93 95% CI 1.14–3.28Authors' conclusion
In patients with CS, RBBB was an independent predictor of SVAEs, which might reflect the specific scar distribution that is predominant in the IVS.
Study context
- Population
- Japanese patients with cardiac sarcoidosis66 with SVAE
- Participants
- 312 patients
- Comparison
- Right bundle branch block (RBBB) vs no RBBB at diagnosis
- RBBBn = 155
- Primary endpoint
- Serious ventricular arrhythmia events:
- SCD
- Documented VF
- Sustained VT
- Appropriate ICD therapy
- Follow-up
- Median 3.0 years (IQR: 1.6-6.0 years)
Methodological detailsmulticentre
- Multicentre
Primary result
As reported in the abstract
Hazard ratio
1.93
95% CI 1.14–3.28
P = 0.015
RBBBvs Non-RBBB
HR 1.93 (95% CI 1.14–3.28); P = 0.015
Further findings
Basal interventricular septum (IVS) thinning and prominent LGE in basal IVS on CMR
- Higher prevalence in RBBB than non-RBBB
Original publication
Association Between Right Bundle Branch Block and Ventricular Arrhythmia in Patients With Cardiac Sarcoidosis. JACC Adv. Published 12 July 2024. doi:10.
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