Arrhythmias & electrophysiology

Daytime Napping, Incident Atrial Fibrillation, and Dynamic Transitions With Dementia

JACC AdvPublished Prospective cohort study

Main finding · Incident AFResult — go to the resultHazard ratio 1.17 95% CI 1.12–1.22

Study context

Population
UK Biobank participantsUK Biobank
Participants
476,588 participants
Exposure
Frequent daytime napping vs never/rarely napping
Outcome
Incident AF
Methodological detailsmultistate survival analysis, mediation analysis
  • Multistate survival analysis
  • Mediation analysis

Main finding

As reported in the abstract

Hazard ratio

1.17

95% CI 1.12–1.22

Frequent nappingvs Never/rarely
HR 1.17 (95% CI 1.12–1.22)

Observational data: associations, not effects.

Further findings

Mediation of napping–atrial fibrillation (AF) association by LVEF

Proportion mediated by LVEF
26.2% (95% CI: 4.2%-74.1%)

Transition from AF to comorbid AF and dementia

Frequent napping associated with 1.27-fold risk of transition

Original publication

Daytime Napping, Incident Atrial Fibrillation, and Dynamic Transitions With Dementia. JACC Adv. Published 12 July 2024. doi:10.1016/j.jacadv.2024.101108

Composed by AI from the published abstract and checked against it. How Briefs are made →

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