Association of admission frailty and frailty changes during cardiac rehabilitation with 5-year outcomes
Authors' conclusion
Frailty status at CR admission was related to long-term adverse outcomes. Frailty improvements during CR were associated with delayed all-cause hospitalization, in which a larger effect was associated with a greater chance of improved outcome.
Study context
- Population
- Patients admitted to a 12-week cardiac rehabilitation (CR) programme in Halifax, Nova Scotia, May 2005–April 2015
- Participants
- 3,371 patients
- Exposure
- Admission frailty and frailty changes during CR vs 5-year outcomes
- Outcome
- Time to mortality, first hospitalization, first emergency department (ED) visit; number of hospitalizations, hospital days and ED visits (all causes and CVD)
- Follow-up
- 5 years
Methodological detailslinked administrative health data, 25-item frailty index (FI) at CR admission and completion; Cox, Fine-Gray and negative binomial hurdle models
- Linked administrative health data
- 25-item FI at CR admission and completion; Cox, Fine-Gray and negative binomial hurdle models
Main finding
As reported in the abstract
Admission FIEstimate (95% CI)
Time to all-cause hospitalization
HR 1.02(1.01,1.02)
Time to CVD hospitalization
HR 1.02(1.01,1.02)
Number of all-cause hospitalizations
IRR 1.02(1.01,1.03)
All-cause hospital days
IRR 1.01(1.01,1.03)
Number of all-cause ED visits
IRR 1.02(1.02,1.03)
Observational data: associations, not effects.
Further findings
FI improvement during CR and 5-year outcomes
- FI improvements not associated with other outcomes
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Association of admission frailty and frailty changes during cardiac rehabilitation with 5-year outcomes. Eur J Prev Cardiol. Published 17 February 2023. doi:10.
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