Arrhythmias & electrophysiology
Association of Atrial Fibrillation Symptom Burden With Social Determinants of Health
Authors' conclusion
After adjusting for clinical factors, adverse SDoH associate with blunted improvements in AF symptom burden after 1 year of clinical management.
Study context
- Population
- Patients referred with an initial diagnosis of paroxysmal or persistent atrial fibrillation (AF) at a US academic medical centre serving predominantly low-income and underinsured populationswith follow-up assessments
- Participants
- 515 patients
- Exposure
- Adverse social determinants of health (SDoH) vs less adverse SDoH
- Outcome
- AFEQT score (higher = better quality of life)
- Follow-up
- 1 year
Methodological detailsobservational, single academic medical centre
- Observational
- Single academic medical centre
Main finding
As reported in the abstract
Change in AFEQT score
Difference, points (95% CI)
Higher NDIvs Lower NDI
6.4(1.9–11.0)
Non-Hispanic Blackvs Non-Hispanic White
4.6(1.1–8.0)
Observational data: associations, not effects.
Further findings
AFEQT score, whole cohort
- Mean AFEQT score at baseline (of 100)
- 73
- Mean AFEQT score at follow-up (SD 19)
- 80
Safety
Clinical events
- Admissions for decompensated HF
- 61
- Ischemic strokes
- 53
- All-cause mortality events
- 47
Original publication
Association of Atrial Fibrillation Symptom Burden With Social Determinants of Health. JACC Adv. Published 6 November 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →