Arrhythmias & electrophysiology
Drug-coated balloon venoplasty for symptomatic lead-related venous stenosis
Authors' conclusion
DCB venoplasty is a safe, effective treatment for symptomatic LRVS, providing durable symptom relief even in the presence of retained transvenous leads. Compared with traditional balloon venoplasty, DCB use was associated with improved long-term outcomes, including higher success rates after a single procedure.
Study context
- Population
- Patients with symptomatic lead-related venous stenosis (LRVS), single tertiary centre, 2022–2025
- Participants
- 15 patients18 DCB procedures
- Exposure
- DCB venoplasty vs traditional percutaneous balloon venoplasty
- DCBn = 15
- Outcome
- Long-term success rate of a single procedure with leads remaining
- Follow-up
- Long-term
Methodological detailssingle-centre, historical control cohort
- Single-centre
- Historical control cohort
Main finding
As reported in the abstract
Long-term single-procedure success with leads remaining: DCB vs historical cohort treated with traditional balloons
71% vs 33%
Observational data: associations, not effects.
Further findings
Leads remaining across the stenosis
P ≤ 0.01
| Outcome | DCB | Traditional balloons |
|---|---|---|
| Complete symptom resolutionPer case | 87% | — not stated in the abstract |
— not stated in the abstract
Complete symptom resolution
- Remainder had persistent symptoms attributed to secondary lymphedema
Lead extraction and lead retention
- Lead extraction required
- 11%
- Retained leads across the treated segment
- 93%
Original publication
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