Acute cardiac care & resuscitation

Association of blood pressure with neurologic outcome at hospital discharge after pediatric cardiac arrest resuscitation

ResuscitationPublished Retrospective cohort study

Corrected 23 Oct 2026: The values shown beside the odds ratios were the share of patients in each blood-pressure group, not the outcome's rate; removed.

Authors' conclusion

In the first 6-hours post-ROSC, a lowest documented MAP between the 5th-74th percentile for age was associated with favorable neurologic outcome compared to MAP <5th percentile for age.

Study context

Population
Children (<18 years) with return of spontaneous circulation (ROSC) after index in-hospital or out-of-hospital cardiac arrest who survived ≥6 hours (pediRES-Q); lowest mean arterial pressure (MAP) within first 6 hours of ROSC
Participants
787 children
Exposure
Lowest MAP percentile groups vs MAP <5th percentile for age
Outcome
Favorable neurologic status (PCPC score 1, 2, or no change from pre-arrest baseline)
Follow-up
Hospital discharge
Methodological detailsmulticentre, observational
  • Multicentre
  • Observational

Main finding

As reported in the abstract

Favourable neurologic outcome at hospital discharge
Each group vs IAdjusted odds ratio (95% CI)
II
1.84(1.24–2.73)
III
2.20(1.32–3.68)
IV
1.90(1.12–3.25)
Vno association
1.44(0.75–2.80)
VIno association
1.11(0.47–2.59)

Observational data: associations, not effects.

Further findings

OutcomeValues
Median lowest MAP percentile, by outcome · first 6 hours of ROSCUnfavorable outcome median 8 (IQR 1,37) percentile

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Association of blood pressure with neurologic outcome at hospital discharge after pediatric cardiac arrest resuscitation. Resuscitation. Published 4 December 2023. doi:10.1016/j.resuscitation.2023.110066

Summarised from the published abstract; every number is checked against it

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